23S rRNA (guanine2535-N1)-methyltransferase (, AviRa) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2535-N1)-methyltransferase. This enzyme catalyses the following chemical reaction
S-adenosyl-L-methionine + guanine2535 in 23S rRNA S-adenosyl-L-homocysteine + N1-methylguanine2535 in 23S rRNA
This is one of the methyltransferases from Streptomyces viridochromogenes . Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis.
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