Braine is a surname. Notable people with the surname include:
Bernard Braine (1914–2000), British politician Daniel L. Braine (1829–1898), American naval admiral David Braine (philosopher) (born 1940), British philosopher David Braine (athletic director) (born 1943), athletic director Jehan de Braine (c. 1200–1240), Count of Macon and Vienne John Braine (1922–1986), English novelist Martin Braine (1926–1996), British, American psychologist Pierre Braine (1900–1951), Belgian footballer Raymond Braine (1907–1978), Belgian footballer Richard Braine (actor) (born 1956), British actor Richard Braine (politician) (born 1968), British politician, leader of the UK Independence Party (UKIP) Robert Braine (1896–1940), American composer