Bourguignon is a French surname. Notable people with the surname include:
André Bourguignon (1920–1996), French psychiatrist Anne Bourguignon, French actress, known as Anémone (1950–2019), daughter of André François Bourguignon (born 1945), French economist Giulia Bourguignon Marinho, known as Giulia Be (born 1999), Brazilian singer Erika Bourguignon (1924–2015), American anthropologist Jean-Pierre Bourguignon (born 1947), French mathematician Louis Dominique Bourguignon (18th century), French highwayman Philippe Bourguignon (born 1948), French businessman