23S rRNA (adenine1618-N6)-methyltransferase (, rRNA large subunit methyltransferase F, YbiN protein, rlmF (gene), m6A1618 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine1618-N6)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine1618 in 23S rRNA S-adenosyl-L-homocysteine + N6-methyladenine1618 in 23S rRNA

The recombinant YbiN protein is able to methylate partially deproteinized 50S ribosomal subunit.

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