The 2010 Novilon Eurocup Ronde van Drenthe was the 12th running of the Damesronde van Drenthe, a women's bicycle race in Drenthe, the Netherlands. It was held on 11 April 2010 over a distance of . It was rated by the UCI as a 1.1 category race.

Results CyclistTeamTime1 Nederland Bloeit 3h 33' 17"2 Team HTC-Columbia Women + 21"3 Cervélo Test Team + 21"4 Nederland Bloeit + 21"5 Red Sun Cycling Team + 21"6 Cervélo Test Team + 31"7 Cervélo Test Team + 1' 29"8 Lotto Ladies Team + 1' 29"9 Lotto Ladies Team + 1' 29"10 Team HTC-Columbia Women + 1' 29" Source

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