Limonene 1,2-monooxygenase () is an enzyme with systematic name limonene,NAD(P)H:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction

(1) (S)-limonene + NAD(P)H + H+ + O2 1,2-epoxymenth-8-ene + NAD(P)+ + H2O (2) (R)-limonene + NAD(P)H + H+ + O2 1,2-epoxymenth-8-ene + NAD(P)+ + H2O

Limonene 1,2-monooxygenase flavoprotein (FAD).

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