CLK-1, clk1, or variation, may refer to:

, post-World War II light cruiser reclassified as a destroyer leader (DL) clk-1 (gene), the clock-1 gene for ubiquinone biosynthesis encoding DMQ hydroxylase CLK1 (protein), the human enzyme dual specificity protein kinase CLK1, encoded by the CLK1 gene

See also

CLK (disambiguation)