The Agony and the Ecstasy may refer to:

The Agony and the Ecstasy (novel), a 1961 novel by Irving Stone about the painter Michelangelo The Agony and the Ecstasy (film), a 1965 film starring Charlton Heston, partly based on the novel The Agony and the Ecstasy (album), a 2012 release by High Contrast "The Agony and the Ecstasy", a song by Smokey Robinson from the 1975 album A Quiet Storm The Agony and the Ecstasy cartoon series featuring Lobster Random The Agony and the Ecstasy, 2012 exhibition by artist Parker Ito

See also Drunk on the Pope's Blood/The Agony Is the Ecstacy, 1982 EP by The Birthday Party and Lydia Lunch The Agony Without the Ecstasy, 2000 EP by Fosca Agony and Ecstasy: My Life in Dance, autobiography of Czech ballet dancer Daria Klimentová