Menaquinol oxidase (H+-transporting) (, cytochrome aa3-600 oxidase) is an enzyme with systematic name menaquinol:O2 oxidoreductase (H+-transporting). This enzyme catalyses the following chemical reaction

2 menaquinol + O2 2 menaquinone + 2 H2O

Cytochrome aa3-600, one of the respiratory oxidases from Bacillus subtilis, is a member of the heme-copper family of oxygen reductases.

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