Piesse is a surname. Notable people with the surname include:
Alfred Piesse (1866–1939), Australian politician Arnold Piesse (1872–1935), Australian politician Bonnie Piesse (born 1983), Australian actress and musician Charles Piesse (1855–1914), Australian politician Edmund Piesse (1900–1952), Australian politician Frederick Henry Piesse (1853–1912), Australian politician Frederick William Piesse (1848–1902), Australian politician George William Septimus Piesse (1820–1882), English chemist and perfumer Harold Piesse (1884–1944), Australian politician Ken Piesse (born 1955), Australian journalist Paul Piesse, New Zealand politician Winifred Piesse (1923–2017), Australian politician
See also Piesse Brook, Western Australia