Soluble quinoprotein glucose dehydrogenase (, soluble glucose dehydrogenase, sGDH, glucose dehydrogenase (PQQ-dependent)) is an enzyme with systematic name D-glucose:acceptor oxidoreductase. This enzyme catalyses the following chemical reaction

This soluble periplasmic enzyme contains PQQ as prosthetic group, and is bound to a calcium ion. The electron acceptor is not known.

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