The 2010–11 season was Panionios' 50th season in Super League Greece. They also competed in the Greek Football Cup.
Current squad
Transfers
In Time Pos. Name From Fee Summer DF Patrick Phungwayo Bidvest Wits Loan Summer MF Jahmir Hyka Mainz €105.600 Summer MF Maxime Partouche Paris Saint-Germain Free Summer FW Mohamed Chalali Châteauroux Free Summer MF Kasper Risgård Arminia Bielefeld Free Summer DF Solomon Okpako Kano Pillars Free Summer GK Jürgen Macho LASK Linz Free Summer DF Cédric Varrault Saint-Étienne Free Summer FW Ricardo Vaz Tê Bolton Free Summer MF Isaac Pupo Mughan Free Summer MF Dimitrios Kiliaras Ergotelis Return From Loan Summer DF Andreas Iraklis Kallithea Return From Loan Summer DF Mehmet Hetemaj AlbinoLeffe Return From Loan Winter FW Konstantinos Mitroglou Olympiacos Loan Winter DF Georgios Galitsios Olympiacos Loan Winter FW Václav Svěrkoš Sochaux Loan Winter DF Dato Kvirkvelia Rubin Kazan Free Winter GK Markus Pröll – –
Out Time Pos. Name To Fee Summer DF Georgios Tzavelas Eintracht Frankfurt €1.056.000 Summer FW Bédi Buval Lechia Gdańsk Free Summer DF Mehmet Hetemaj AlbinoLeffe €105.600 Summer GK Charalambos Tabasis Diagoras Free Summer GK Kostas Andriolas Panthrakikos Free Summer MF Marios Nicolaou AEL Limassol Free Summer MF Manolis Skoufalis PAS Giannina Free Summer DF Theodoros Santamouris Agia Paraskevi Free Summer FW Giannis Simosis Panthrakikos Free Summer DF Nikolaos Lazouras Keravnos Keratea Free Summer MF Christos Maniatis Keravnos Keratea Free Summer DF Andreas Iraklis Kallithea Free Summer MF Fabián Estoyanoff Peñarol Loan Summer FW Giannis Loukinas AEL Kalloni Loan Summer MF Carlos Casteglione Arsenal Sarandí End of Loan Summer DF Wellington Baroni Espanyol End of Loan Summer GK Isaac Becerra Espanyol B End of Loan Winter DF Ioannis Maniatis Olympiacos Winter MF Jahmir Hyka KF Tirana €61.600 Winter GK Tomáš Belic FK Púchov Free Winter MF Dimitrios Kiliaras Levadiakos Free Winter DF Patrick Phungwayo Bidvest Wits End of Loan Winter FW Ricardo Vaz Tê Hibernian Free Winter FW Vasil Shkurti Thrasyvoulos Loan Winter FW Giannis Loukinas PAO Rouf Loan Winter MF Christos Kontochristos Nafpaktiakos Asteras Loan Winter DF Solomon Okpako Mamelodi Sundowns Free Winter MF Isaac Pupo Hammarby Free
Matches
Super League
Greek Cup
Top goalscorers 8 goals Kostas Mitroglou (8 in Super League) 4 goals Boško Balaban (4 in Super League) 3 goals Sito Riera (2 in Super League, 1 in Greek Cup) 2 goals Dimitris Siovas (2 in Super League) Georgios Galitsios (2 in Super League) 1 goal Bennard Kumordzi (1 in Super League) Ricardo Vaz Tê (1 in Super League) Giannis Maniatis (1 in Super League) Andreas Samaris (1 in Super League) Davor Kukec (1 in Super League) Václav Svěrkoš (1 in Super League) Fanouris Goundoulakis (1 in Super League)