Tyus is a given name and surname. Notable people with the name include:
Surname Alex Tyus (born 1988), American-Israeli basketball player Anthony Tyus III (born 2003), American football player Leroy Tyus (1916–1998) American politician and real estate developer Tina Tyus-Shaw, American television news anchor and journalist Wyomia Tyus, American athlete
Given name Tyus Battle, American basketball player Tyus Bowser, American football player Tyus Edney, American basketball coach and former player Tyus Jackson, American football linebacker Tyus Jones, American basketball player
See also Tyus, Perm Krai, a locality in Russia Tyus, Georgia, a community in the United States