Rupert II may refer to:
Rupert II, Count of Laurenburg (died c. 1159) Rupert II, Elector Palatine (1325–1398) Rupert II of Lubin (1396/1402 – 1431) Rupert of Palatinate-Simmern (1461–1507), 45th bishop of Regensburg (with Rupert of Palatinate-Mosbach as Rupert I)