The men's T42-46 event at the 2008 Summer Paralympics took place at the Beijing National Stadium on 16 September 2008. There were no heats in this event.

Results Final Competed at 19:45. Rank Nation Swimmers Time Notes Jim Bob Bizzell Brian Frasure Casey Tibbs Jerome Singleton 42.75 WR Andre Luiz Oliveira Yohansson Nascimento Claudemir Santos Alan Oliveira 45.25 Heath Francis Stephen Wilson Aaron Chatman Paul Raison 45.80 4 Xavier le Draoullec Arnaud Assoumani Serge Ornem Clavel Kayitaré 46.68 Naohiro Ninomiya Tomoki Tagawa Toru Suzuki Atsushi Yamamoto DQ

WR = World Record. DQ = Disqualified (passing of the baton outside the take-over zone).

References Official Beijing 2008 Paralympics Results: Final