Piko may refer to:

PIKO, a model train manufacturer Piko Interactive, an American game developer and publisher. Piko (singer) (b. 1988), a Japanese pop singer Piko (Filipino game), a Filipino children's game similar to hopscotch Piko, renamed Penny in English dubbing, a character from the anime Stitch! Piko (wrestler), a Japanese professional wrestler Utatane Piko, a vocaloid from Sony Entertainment

See also Pico (disambiguation)