Van Hook or VanHook is a surname. Notable people with the surname include:
Caroline van Hook Bean (1879–1980) American painter Clay Van Hook (born 1985), American basketball coach Forest Van Hook (1883–1937), American football player Kendall Vanhook Bumpass (1809–1885) American pioneer Kevin VanHook (born 1965), American comics writer and film director Loretta C. Van Hook (1852–1935), American missionary and educator Robert Van Hook (1960–2018), American convicted murderer executed in Ohio
See also Van Hook Township, Mountrail County, North Dakota, township in the United States Van Hook, North Dakota, ghost town in the United States Van Hook State Wildlife Management Area