First Gentleman of Tanzania or First Lady of Tanzania is the unofficial title held by the husband or wife of the president of Tanzania. Until 19 March 2021, the position was held by women and thus referred to as First Lady until Hafidh Ameir Hassan, the husband of Samia Suluhu Hassan and the country's inaugural First Gentleman, took the role until his death in 2026.

Present and former Tanzanian first ladies are often affectionately called "Mama" within the country. In recent years, there has been public debate over the increasingly prominent role of the first ladies and gentlemen of Tanzania. There have been calls for Parliament to formalize the office of the first lady and first gentleman of Tanzania.

First ladies and gentlemen of Tanzania # First Lady/First GentlemanBorn/Died Portrait Date tenure began Date tenure ended President (Husband or wife) Notes 01.01 Maria Nyerere (born 1930) 1 November 1964 5 November 1985 Julius Nyerere 02.02 Siti Mwinyi (born 1932) 5 November 1985 23 November 1995 Ali Hassan Mwinyi 03.03 Anna Mkapa (born ?) 23 November 1995 21 December 2005 Benjamin Mkapa 04.04 Salma Kikwete (born 1963) 21 December 2005 5 November 2015 Jakaya Kikwete 04.05 Janeth Magufuli (born 1960) 5 November 2015 17 March 2021 John Magufuli 04.06 Hafidh Ameir Hassan (1946–2026) 19 March 2021 7 September 2026 Samia Suluhu Hassan Tanzania's inaugural First Gentleman. Died on 7 September 2026.

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