Ottesen is a surname. Notable people with the surname include:
Camilla Ottesen (born 1972), Danish television presenter Carl Ottesen (1918–1972), Danish actor, screenwriter and film director Elise Ottesen-Jensen (1886–1973), Norwegian-Swedish sex educator, journalist and anarchist agitator Jacob Aaal Ottesen Preus III (1953–2022), former president of Concordia University in Irvine, California Jacob Aall Ottesen Preus (1883–1961), American politician Jacob Aall Ottesen Preus II (1920–1994), Lutheran pastor, professor, author, and church president Jakob Aall Ottesen Larsen (1888–1974), an American classical scholar Marian Saastad Ottesen (born 1975), Norwegian actress Janove Ottesen (born 1975), Norwegian musician Jeanette Ottesen (born 1987), Danish swimmer Lasse Ottesen (born 1974), Norwegian former ski jumper Realf Ottesen Brandt (1859–1927), American Lutheran minister Sölvi Ottesen (born 1984), Icelandic footballer Tyge Ottesen Brahe (1546–1601), Danish nobleman known for his accurate and comprehensive astronomical and planetary observations