Loeser is a surname. Notable people with the surname include:

Arthur E. Loeser (1903–1942), appointed to the United States Naval Academy on 15 August 1923 Ewald Loeser (1888–1970), German lawyer François Loeser (born 1958), French mathematician Hans F. Loeser (1920–2010), American lawyer Wilhelm Loeser (1876–1953), American physician and pharmacist