Villaume or Villaumé is a surname. Notable people with the surname include:
Astrid Villaume (1923–1995), Danish actress Emmanuel Villaume (born 1964), French conductor Farid Villaume (born 1975), French Muay Thai kickboxer Henri La Fayette Villaume Ducoudray Holstein (1772–1839), American writer, journalist and French army officer in the Napoleonic Wars Jean-Michel Villaumé (born 1946), French politician William Villaume (1914–1995), American Lutheran clergyman