McKain is a surname. Notable people with the surname include:
Archie McKain (1911–1985), American baseball player Devante McKain (born 1994), English footballer Douglas Mary McKain (1789–1873), New Zealand nurse, midwife and businesswoman Hal McKain (1906–1970), American baseball player Jonathan McKain (born 1982), Australian footballer
See also
McKane (surename) McKean (surename) McCain (surename)