Wolfgang Axel Tomé is a German American physicist working in medicine as a researcher, inventor, and educator. He is noted for his contributions to the use of optically guided patient positioning techniques in high precision radiation therapy; his work on risk adaptive radiation therapy which is based on the risk level for recurrence in tumor sub-volumes using biological objective functions; the development of hippocampal avoidant cranial radiation therapy techniques to alleviate hippocampal-dependent neurocognitive impairment following cranial irradiation; and the invention of temporally modulated pulsed radiation therapy for the treatment of tumors exhibiting low dose hyper-radiation sensitivity.
Tomé is the author of Path Integrals on Group manifoldsTomé W. (1998). Path Integrals on Group Manifolds: The Representation Independent Propagator for General Lie Groups. New York: World Scientific Publishing Company. and co-author of Dose Painting IMRT Using Biological Parameters.Kim Y. and Tomé W. (2014). Dose Painting IMRT Using Biological Parameters. Saarbrücken: Scholars' Press. He serves as Professor in the Departments of Radiation Oncology and Neurology at the Albert Einstein College of Medicine. Prior to this appointment, he served as Professor in the Departments of Medical Physics, Human Oncology, and Biomedical Engineering at the University of Wisconsin–Madison. In 2025, he was awarded Professor Emeritus status by the University of Wisconsin. Together with Anatoly Pinchuk and Jamey Weichert, he is an inventor of long-lived tumor-specific Gadolinium-based agents for imaging and therapy.Patent No. US 10,265,398 B2. He has published more than 300 articles in medical and mathematical physics.https://www.ncbi.nlm.nih.gov/myncbi/1F3lwzezjNXsw7/bibliography/public/[https://mathscinet.ams.org/mathscinet/MRAuthorID/328492 He is also credited on 11 patents.Patent No. US 6,974,254 B2; Patent No. US 7,508,967 B2; Patent No. US 7,551,717 B2; Patent No. US 8,526,692 B2; Patent No. US 8,897,857 B2; Patent No. WO2012069965 A1; Patent No. US 10,007,961 B2; Patent No. MX2017004402A; Patent No. US 10,265,398 B2; Patent No. 11,612,716 B2. In addition, he has participated in several AAPM task groups,AAPM TG 101: Stereotactic Body Radiation Therapy (SBRT); AAPM TG 147: QA for non-radiographic localization and positioning systems; AAPM TG 154: Quality Assurance of Ultrasound Guided Radiotherapy; and AAPM TG 302: Surface Image Guided Radiotherapy. including the AAPM Working Group on Biological Effects of Hypofractionated Radiotherapy/SBRT.
In recognition of his contributions to the fields of medical physics and radiation oncology he been made a Fellow of the American Association of Physicists in Medicine (FAAPM) in 2010, and Fellow of the American Society for Radiation Oncology (FASTRO) in 2017.
References
External links Wolfgang A. Tomé profile at Albert Einstein College of Medicine