Mkrtchyan or Mkrtchian (, ) is an Armenian surname. Notable people with the surname include:
Aghvan Mkrtchyan (born 1981), Armenian football defender Albert Mkrtchyan (1937–2018), Armenian film director Anatoly Mkrtchyan (1931–2012), Armenian politician Armen Mkrtchyan (born 1973), Armenian wrestler Arthur Mkrtchyan (born 1973), retired Armenian football defender Artur Mkrtchyan (1959–1992), the First Chairman of Supreme Council of the Nagorno-Karabakh Republic Artur Mkrtchyan (wrestler), Armenian Greco-Roman wrestler Hakob Mkrtchyan (born 1997), Armenian male weightlifter Karlen Mkrtchyan (born 1988), Armenian football midfielder Karo Mkrtchyan (1951–2001), Armenian painter and public figure Levon Mkrtchyan (born 1953), Armenian director known for documentaries Lilit Mkrtchian (born 1982), Armenian grandmaster and four-time Armenian Women's champion Lilit Mkrtchyan (shooter) (born 1996), Armenian sports shooter Margarita Mkrtchyan (1981–2013), Russian taekwondo practitioner Mariam Mkrtchyan (born 2004), Armenian chess player Mger Mkrtchyan (born 1976), Armenian boxer Mher Mkrtchyan, multiple people Narek Mkrtchyan (born 1989), Armenian politician Rudik Mkrtchyan (born 1993), Armenian Greco-Roman wrestler Samvel Mkrtchyan (1959–2014), Armenian translator, editor and writer Sassun Mkrtchyan (1989–2016), Armenian contract serviceman, scout and machine-gunner Sergey Mkrtchyan (born 2001), Armenian football player Styopa Mkrtchyan (born 2003), Armenian footballer Susanna Mkrtchyan (born 1949), Armenian professor and founder of Wikimedia Armenia Tigran Mkrtchyan (born 1978), Armenian diplomat, historian and political scientist Yervand Mkrtchyan (born 1996), Armenian middle and long-distance runner
See also Makran Mkrtich Ter-Mkrtychyan