Holtbyrnia is a genus of deepwater marine ray-finned fishes belonging to the family Platytroctidae, the tubeshoulders. The fishes in this genus are found in the Eastern Atlantic Ocean, the Indo-West Pacific and the southeastern Pacific Ocean.

Species There are currently ten recognized species in this genus: Holtbyrnia anomala Krefft, 1980 (Bighead searsid) Holtbyrnia conocephala Sazonov, 1976 Holtbyrnia cyanocephala (Krefft, 1967) Holtbyrnia innesi (Fowler, 1934) (Teardrop tubeshoulder) Holtbyrnia intermedia (Sazonov, 1976) Holtbyrnia laticauda Sazonov, 1976 (Tusked tubeshoulder) Holtbyrnia latifrons Sazonov, 1976 (Streaklight tubeshoulder) Holtbyrnia macrops Maul, 1957 (Bigeye searsid) Holtbyrnia melanocephala (Vaillant, 1888) Holtbyrnia ophiocephala Sazonov & Golovan, 1976

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