Li Gu may refer to:
Li Gu (Han dynasty) (李固; 93–147), courtesy name Zijian (子堅), Eastern Han dynasty scholar and official Li Gu (Later Zhou) (李穀; 903–960), Later Zhou dynasty chancellor Li Gu (李固), fictional character in the novel Water Margin, Lu Junyi's housekeeper who betrayed his master
See also Gu Li (disambiguation) for people surnamed Gu