The J. B. Milleysack Cigar Factory is an historic cigar factory which is located in Lancaster, Lancaster County, Pennsylvania, United States.

It was listed on the National Register of Historic Places in 1990.

History and architectural features Built in 1898, this historic structure is a three-story, rectangular, red brick building which sits on a stone foundation. It is three bays by four bays and has a shed-type roof. The building was damaged by fire in January 1990, and subsequently restored. It housed a cigar factory and later a toy manufacturer. ()

It was listed on the National Register of Historic Places in 1990.

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