The 1920–21 season was the 24th in the history of the Western Football League.

The Division One champions this season were Bristol City Reserves, for the second time in their history. Champions of Division Two were Peasedown St John, who gained promotion to Division One along with Trowbridge Town.Robinson, Michael (ed.), Non-League Football Tables 1889–2006, Soccer Books, 2006

Division One Eight new clubs joined Division One this season, and the number of clubs increased from 10 to 16 after Horfield United and Newport County Reserves left the league. Abertillery Town Cardiff City Reserves, rejoining the league after leaving in 1914 Cardiff Corinthians Exeter City Reserves Mid Rhondda Pontypridd Ton Pentre, rejoining the league after leaving in 1910 Yeovil and Petters United, promoted from Division Two

Abertillery Town, Mid Rhondda, Pontypridd and Ton Pentre were also members of the Southern League (Welsh section) during this season. All four clubs left the Western League at the end of the season to concentrate on the Southern League.

Division Two Three new clubs joined Division Two this season, and the number of clubs increased from eight to ten after Yeovil and Petters United were promoted. Clandown Radstock Town, rejoining the league after leaving in 1910 Welton Amateurs

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