The 2012 Lafayette Leopards football team represented Lafayette College as member of the Patriot League during the 2012 NCAA Division I FCS football season. Led by 13th-year head coach Frank Tavani, the Leopards compiled an overall record of 5–6 with a mark of 2–4 in conference play, placing in a three-way tie for third in the Patriot League. Lafayette played home games at Fisher Field in Easton, Pennsylvania.

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