Chaine is a surname. Notable people with the surname include:
People Francis Chaine (born 1921), Hong Kong lawyer and politician Guillaume Chaine (born 1986), French judoka James Chaine (1841–1885), Irish shipping businessman and a Conservative Party politician Chaine Memorial, a memorial to James Chaine John Chaine, Irish Anglican priest Robert McCalmont (1881–1953), Northern Irish unionist politician and British Army officer Sipho Chaine (born 1996), South African soccer player William Chaine (1838–1916), British military officer and courtier
See also Kent DuChaine (born 1951), American blues singer and guitarist