is Italian for 'Holy Cross' and may refer to:
Santa Croce (Venice), one of the six (districts) of Venice, Italy. The Pontifical University of the Holy Cross () in Rome, Italy. Many churches, including: Santa Croce, Florence, built 1294–1385 and the burial place of several notable Italians Santa Croce della Foce, Gubbio, Umbria, built in the 13th century Basilica di Santa Croce (Lecce), built 1549–1646 Santa Croce, Parma, built 1222–1666 Santa Croce, Padua, built 1737–1749 Santa Croce in Fossabanda, Pisa, built 1325–19th century Santa Croce e San Bonaventura alla Pilotta, Rome, built 1625–19th century Santa Croce in Gerusalemme, Rome, consecrated around 325 Santa Croce alla Lungara, Rome, consecrated 1619 Santa Croce degli Armeni, Venice, built 13th century, consecrated 1688 Santa Croce in Via Flaminia, Rome, built 1913, consecrated 1981
People House of Santacroce, a noble Roman family. To this belongs among others: Prospero Santacroce, 16th-century cardinal Cecilia Santacroce (born 1990), Italian archer Fabiano Santacroce (born 1986), Italian-Brazilian football player Isabella Santacroce (born 1970), Italian novelist Girolamo Santacroce, a 16th-century Italian sculptor and painter
Places Santa Croce sull'Arno, town in Tuscany Santa Croce Camerina, town in Sicily
Villages Santa Croce di Magliano, a commune in Campobasso, Molise Santa Croce di Roccaromana, a commune in Caserta, Campania Santa Croce del Sannio, a commune in Benevento, Campania
See also Santa Cruz (disambiguation) Sainte-Croix (disambiguation) Holy Cross (disambiguation)