Santiago District may refer to: Santiago District, Palmares, Alajuela Province, Costa Rica Santiago District, San Ramón, Alajuela Province, Costa Rica Santiago District, Puriscal, San José Province, Costa Rica Santiago District, San Rafael, Heredia Province, Costa Rica Santiago District, Paraíso, Cartago Province, Costa Rica Santiago District, Veraguas, Panama Santiago District, Paraguay, Misiones Department Santiago District, Cusco, Peru Santiago District, Ica, Peru
See also Río Santiago District