Cilliers is a surname. Notable people with the surname include:

Cecile Cilliers (1933–2018), Afrikaans writer Charl Cilliers (writer) (born 1941), South African author and poet Ina Cilliers (born 1969), South African politician Jana Cilliers (born 1950), South African actress Ockert Cilliers (born 1981), South African hurdler Pat Cilliers (born 1987), South African rugby union footballer Paul Cilliers (Friedrich Paul Cilliers, 1956–2011), South African philosopher Raymond Cilliers (born 1981), South African Christian recording artist Sarel Cilliers (Charl Arnoldus Cilliers, 1801–1871), Voortrekker leader and a preacher Victoria Cilliers, British skydiver who survived a murder attempt on her in 2015 Vlok Cilliers (born 1968), South African rugby union player

See also Charl Cilliers (disambiguation)