Eighth and Center Streets Baptist Church is a historic African-American Baptist church located at 722 Center Street in Hannibal, Marion County, Missouri. Built in 1872, the church is a red brick, two-level rectangular Romanesque Revival building measuring approximately 70 feet long by 40 feet wide. (includes 3 photographs from 1979)

In 1980, it was listed on the National Register of Historic Places. It is located in the Central Park Historic District and Maple Avenue Historic District.

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