Gigliotti () is an Italian surname from Catanzaro, probably derived from the medieval masculine name Giglio. Notable people with the surname include:

Anthony Gigliotti (1922–2001), American clarinet player and music teacher Bruno Gigliotti (born 1936), known as Orlando, French-Italian singer, actor and record producer Carol Gigliotti, American academic, writer, artist and animal activist David Gigliotti (born 1985), French footballer Denny Gigliotti (born 1991), Italian footballer Donna Gigliotti (born 1955), American film producer Emmanuel Gigliotti (born 1987), Argentine footballer Frank Gigliotti (born 1942), American politician Gilbert L. Gigliotti (born 1961), American literature scholar and academic Guillaume Gigliotti (born 1989), French footballer Iolanda Cristina Gigliotti (1933–1987), known as Dalida, French-Italian singer and actress Lupe Gigliotti (1926–2010), Brazilian actress Paul Gigliotti, Canadian musician

Fictional characters Bobo Gigliotti, character in the Australian film Fat Pizza

See also Metula gigliottii, a species of sea snail Giglioli

References