The year 2012 involved many significant scientific events and discoveries, including the first orbital rendezvous by a commercial spacecraft, the discovery of a particle highly similar to the long-sought Higgs boson, and the near-eradication of guinea worm disease. A total of 72 successful orbital spaceflights occurred in 2012, and the year also saw numerous developments in fields such as robotics, 3D printing, stem cell research and genetics. Over 540,000 technological patent applications were made in the United States alone in 2012.

2012 was declared the International Year of Sustainable Energy for All by the United Nations. 2012 also marked Alan Turing Year, a celebration of the life and work of the English mathematician, logician, cryptanalyst and computer scientist Alan Turing.

Events, discoveries and inventions January

February

March

April

2 April – The British Army announces the development of a conductive smart fabric for infantry uniforms. The fabric, which should enter widespread service by 2015, will eliminate the need for heavy, vulnerable power cables, making soldiers' electronics safer, cheaper and more durable. 4 April A new, detailed record of past climate change has shown compelling evidence that the last ice age was ended by a rise in temperature driven by an increase in atmospheric carbon dioxide. The key result from the new study is that it shows the carbon dioxide rise during this major transition ran slightly ahead of increases in global temperature. Austrian and Japanese researchers unveil solar cells that are thinner than a thread of spider silk, and flexible enough to be wrapped around a single human hair. American researchers begin a new project, funded by the National Science Foundation, to develop printable robots that can be designed and made to order by the average person in less than 24 hours. The project, which is hoped to come to fruition by 2020, could allow any individual to cheaply build automated tools for any task in their own home. 5 April Dutch and American researchers report that they have created a working quantum computer out of diamond, using the diamond's natural impurities as superimposed qubits to perform calculations. Google unveils Project Glass, which aims to develop augmented reality glasses capable of layering information such as email, real-time traffic updates and video calls over a user's field of vision. The Large Hadron Collider re-enters operation after an energy upgrade. It now has a total collision energy of 8 trillion electronvolts, a major increase over its pre-upgrade energy of 7 TeV. 6 April – An international team of researchers reports that a new, drug-resistant strain of malaria has emerged on the Thai–Cambodian border, potentially threatening global efforts to contain the disease. 8 April – American scientists reveal that transparent graphene sheets can be used to encapsulate liquids for study by electron microscopes. The discovery will greatly ease the accurate imaging of liquids at micro- and nanoscales. 10 April – The Wellcome Trust, one of the world's largest private funders of scientific research, states that it is launching a new online journal to promote the free sharing of scientific papers. The new journal, titled eLife, is part of a widespread push for open access to scientific research, and will compel researchers to make their work freely available online. 12 April A team of researchers from France's Laboratoire Univers et Théorie releases the first ever computer model simulation of the structure of the entire observable universe, from the Big Bang to the present day. The simulation has made it possible to follow the evolution of 550 billion individual particles. A report reveals that the United States invested more in renewable energy technology in 2011 than any other nation, totalling US$48 billion. China was the second-largest investor, spending US$45.5 billion on renewables. Worldwide, the combined investment in renewables reached an all-time high, at US$236 billion. A later report published by the United Nations amends these figures, stating that China invested $52 billion in renewable energy in 2011, while the US spent $51 billion. German physicists develop the world's first universal quantum computing network, linking two laboratories using entangled rubidium atoms as network nodes. An international team of researchers has used new, massively parallel DNA sequencing technology to fast-track the discovery of a breast cancer risk gene, XRCC2. DARPA, the US military's advanced research agency, offers a US$2 million prize to any team who can independently develop a rescue robot capable of multiple tasks, including climbing ladders, clearing obstacles, using power tools and driving cars. After studying 40 years of medical records, Swedish scientists state that those with Huntington's disease are around 50% less likely to develop cancer than those without the disease. Further study may reveal the genetic mechanism behind this resistance, allowing new cancer treatments to be developed. The United Kingdom reports that it is considering the installation of undersea power cables to allow its National Grid to draw clean energy from Iceland's volcanoes. Scientists report that complexity analysis studies of the Labeled Release experiments of the 1976 Viking mission to Mars may suggest the detection of "extant microbial life on Mars."

13 April North Korea's Unha-3 orbital rocket disintegrates in mid-flight over the Yellow Sea, destroying its payload, the Kwangmyŏngsŏng-3 satellite. Analysts fear that the failed launch may raise the likelihood of North Korea conducting another nuclear weapons test. German scientists develop a fiber-based "earthquake-proof" wallpaper capable of reinforcing masonry and delaying building collapses during violent quakes. The invention could save lives by giving people more time to flee from collapsing buildings. The Pentagon places an order for advanced dual-focus contact lenses, designed to give soldiers greater visual awareness, in tandem with a new HUD system. The technology may enter the civilian market by 2014. Dutch scientists report that they have found evidence of the existence of the Majorana fermion, a particle that is its own antiparticle. The existence of the Majorana was first theorized by the Italian scientist Ettore Majorana in the 1930s. Researchers at UCLA announce that they have genetically engineered stem cells to seek out and kill HIV in mice. 15 April – Researchers claim that new satellite imagery shows an increase in the mass of some glaciers in Asia's Karakoram mountain range. This data contrasts with the wider global trend of glacial melting. 16 April – A new treatment for prostate cancer can rid the disease from nine in ten men without debilitating side effects, a study has found. 17 April – It is revealed that the Chinese and American militaries have been conducting informal war games together to help prevent military escalation in the event of a future cyber war. 18 April – Researchers at the American National Institutes of Health demonstrate a nanotechnology-based drug treatment which can successfully alleviate some symptoms of cerebral palsy (CP). The drug, which was tested in rabbits, caused a dramatic improvement of the movement disorders and brain inflammation that are characteristic of many cases of CP.

19 April A landmark study by British and Canadian scientists reveals that breast cancer can be subdivided into ten distinct types, with its aggressiveness determined by certain genes. The new data may make breast cancer diagnoses much more precise, and allow cancer treatments to be more effectively tailored to each patient. Led by British scientists, a consortium including American, Belgian and Danish scientists successfully develop synthetic DNA compounds, dubbed "XNA", which demonstrate evolution when faced with selective pressure. British researchers identify key genes that "switch off" as the human body ages. These genes may be targeted by future anti-aging therapies. 20 April Scientists say the notoriously dry continent of Africa is sitting on a vast reservoir of groundwater. A NASA-backed group of universities begins testing a GPS-derived earthquake warning system. The system, which uses satellite data to track seismic activity in real-time, may allow accurate earthquake and tsunami warnings to be issued up to ten times faster than is currently possible. After three years of development, IBM reveals a new, ultra-lightweight lithium-air battery, offering greater energy density than any current lithium-ion battery. The new battery may permit the production of electric vehicles with far greater range and battery life than current models. 21 April – Scientists at Chicago's Northwestern University successfully trial a brain-computer interface capable of restoring naturalistic muscle movements in paralyzed rhesus monkeys. It is hoped the invention will eventually be approved to treat paralytic or brain-damaged humans. 22 April – Intel Corporation releases its new Ivy Bridge microprocessors – the world's first commercial 22 nanometer microchips, featuring increased processing power and energy efficiency. 24 April – Planetary Resources, a startup company backed by Google billionaires Larry Page and Eric Schmidt and film director James Cameron, announces plans to develop technology to survey and mine asteroids for minerals by 2020. The company plans to launch the first element of its project, a network of orbital surveying telescopes, by 2014. 26 April Australian scientists develop a multi-layered, silica-based hydrophobic coating with greater durability than previous such coatings. The invention may be used to make self-cleaning fabrics and antibacterial medical equipment. Researchers develop a crystalline quantum computer, composed of just 300 atoms, that theoretically is so powerful that it would take a conventional computer the size of the known universe to match it. Scientists report that lichen survived over 34 days under Martian conditions in the Mars Simulation Laboratory (MSL) maintained by the German Aerospace Center (DLR). 27 April Researchers identify 53 key neurons in the brains of homing pigeons which may explain how the birds navigate using Earth's geomagnetic field. The British company Reaction Engines begins testing the advanced engine precooler system intended for its reusable Skylon spaceplane. If the tests are successful, the hybrid-rocket Skylon – designed to vastly reduce the cost of orbital spaceflight – may begin flying cargo to Earth's orbit by 2020.

May

1 May Scientists report that a new genetic test could diagnose the risk of breast cancer years before the disease actually develops, allowing much more effective early treatment. French researchers successfully create silicene, a one-atom-thick sheet of silicon that is analogous to the much-vaunted graphene. Silicene is theorized to retain silicon's excellent semiconductor properties even at extremely small scales, and could allow the simple mass production of efficient nanoscale computers. 2 May – The European Space Agency selects the Jupiter Icy Moon Explorer (JUICE) proposal for its next major space exploration program. The robotic JUICE probe, which is planned to launch in 2022, will conduct in-depth studies of the Jovian moons Callisto, Europa and Ganymede. 3 May – In the United Kingdom's first successful ocular implant trial, two men blinded by retinitis pigmentosa have their sight partially restored by prototype microchip implants. 8 May – Claire Lomas, a paralyzed British woman, becomes the first person to complete a marathon using a bionic mobility suit. The ReWalk suit allowed her to complete the London Marathon in 16 days. 9 May – A detailed design is released for a practical artificial leaf – a potentially revolutionary milestone in the development of sustainable energy. 11 May