Castlemaine or Castle Maine may refer to:

Australia Castlemaine, Victoria, a town Castlemaine Football Club, an Australian rules football club Castlemaine railway station Castlemaine Brewery, Western Australia, ceased trading in 1927 Castlemaine Perkins, a Queensland-based brewery, known for the XXXX range of beers , a ship in the Royal Australian Navy

Elsewhere Castlemaine, County Kerry, Ireland, a village Castle Maine, a former castle in the village Baron Castlemaine, in the peerage of Ireland Roger Palmer, 1st Earl of Castlemaine, English courtier Barbara Palmer, 1st Duchess of Cleveland, wife of Roger Palmer