Milesi is an Italian surname. Notable people with the surname include:

Alessandro Milesi (painter) (1856–1945), Italian painter Alessandro Milesi (footballer) (born 1999), Peruvian footballer Davide Milesi (born 1964), Italian runner Giuseppe Milesi Pironi Ferretti (1817–1873), Italian Roman Catholic cardinal Lorenzo Milesi (born 2002), Italian cyclist Luca Milesi (bishop) (1924–2008), Italian-born Eritrean Catholic bishop Luca Milesi (footballer) (born 1993), Italian football player Marco Milesi (born 1970), Italian racing cyclist Piero Milesi (1953–2011), Italian musician

See also