Macropsobrycon is a genus of freshwater ray-finned fish, characins, belonging to the family Characidae. These fishes are found in South America.

Species Macropsobrycon contains the following valid species: Macropsobrycon uruguayanae C. H. Eigenmann, 1915 – Uruguay, Tramandaí and Lagoa dos Patos basins. Macropsobrycon xinguensis Géry, 1973 – Xingu River basin.

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