Alfred Hughes may refer to:
Sports Alfred Hughes (sailor) (1868–1935), British Olympic sailor Alf Hughes (1930–2019), Australian rules footballer Alfredrick Hughes (born 1962), American basketball player
Others Alfred Clifton Hughes (born 1932), retired American prelate of the Roman Catholic Church, Archbishop of New Orleans 2002-2009 Sir Alfred Hughes, 9th Baronet (1825–1898), of the Hughes baronets Alfred W Hughes, served as a surgeon in the Second Boer War, see Hughes Memorial, Corris