James Holburn is the name of:
Sir James Holburn, 1st Baronet (died 1737), of the Holburn baronets Sir James Holburn, 2nd Baronet (died 1758), of the Holburn baronets James Holburn (editor), editor of The Herald
See also James Holborne of Menstrie, Scottish soldier during the years of the English Civil War Holburn (surname)