Bettinelli is a surname. Notable people with the surname include:
Andrea Bettinelli (born 1978), Italian high jumper Bruno Bettinelli (1913–2004), Italian composer Marcus Bettinelli (born 1992), English football player Mario Bettinelli (1880–1953), Italian painter Matt Bettinelli-Olpin (born 1978), American actor Saverio Bettinelli (1718–1808) Italian Jesuit writer