Apollonio may refer to:
Given name Apollonios of Kition, ancient Greek physician Apollonio Buonfratelli, Italian renaissance miniature painter
Surname Giorgia Apollonio (b. 1988), Italian curler Federica Apollonio (b. 1991), Italian curler Nicholas Apollonio, (1843–1911) American baseball franchise owner Zvest Apollonio, (1935–2009) Slovenian painter Giacomo Apollonio, (1584–1654) Italian painter Agostino Apollonio, Italian renaissance painter
See also Apolonio, a 2020 mixtape by Omar Apollo