The First pandemic may refer to:
First plague pandemic (541), also known as the Plague of Justinian First cholera pandemic (1817–1824)
See also "Pandemic" (South Park), 2008 season 12 episode 10, part 1 of 2, preceding the next episode "Pandemic 2" Pandemic (disambiguation) Second pandemic (disambiguation) Third pandemic (disambiguation) Fourth pandemic Fifth pandemic Sixth pandemic Seventh pandemic