GDC may refer to:

Organizations Democratic Group of the Centre (Romanian: ), a political party in Romania Gabriel Dumont College, now Gabriel Dumont Institute, in Saskatchewan, Canada Gambia Democratic Congress, a political party in the Gambia General Development Corporation, a defunct American real estate company General Dental Council in the United Kingdom Genstar Development Company, a Canadian real estate developer Georgia Department of Corrections, of the U.S. state of Georgia Geothermal Development Company, in Kenya Giordano Dance Chicago, an American dance company Government degree colleges in India Gravity Discovery Centre, in Gingin, Western Australia Society of Graphic Designers of Canada Virginia General District Court

Science and technology Gadolinium-doped ceria Game Developers Conference, an annual video game conference Graphic Display Calculator Guglielmi detachable coil GDC, a compiler for the D programming language

Other uses IATA airport code for Donaldson Center Airport, Greenville, South Carolina, United States Gross dealer concession Global Digital Compact, an initiative in the United Nations