Guadalupe District may refer to:
Peru Guadalupe District, Pacasmayo, in Pacasmayo province, La Libertad region
Costa Rica Guadalupe District, Zarcero, in the canton of Zarcero, Alajuela province Guadalupe o Arenilla District, Cartago, in the canton of Cartago, Cartago province Guadalupe District, Goicoechea, in the canton of Goicoechea, San José province
See also Guadalupe (disambiguation)