The 1944–45 Copa Federación de España was the first staging (old competition) of the Copa Federación de España, a knockout competition for Spanish football clubs.

The competition began on 18 February 1945 and ended with the final on 21 May 1945, when San Martín became champion after defeating Valladolid.

Competition

First round

Second round

Fourth round

Fifth round

Sixth Round

Semi-finals

Final