Ratbane, or Rat's bane, may refer to one of the following:

Arsenic trioxide, a poisonous substance Common wintergreen, Pyrola minor, also known as Rat's vein False hellebore, Veratrum viride Gifblaar, Dichapetalum cymosum Helleborine, Epipactis pubescens Pipsissewa plant, Chimaphila umbellata