St. Charles High School may refer to one of several schools in the United States:
St. Charles East High School, public school in St. Charles, Illinois St. Charles North High School, public school in St. Charles, Illinois St. Charles High School (Maryland), public school in Waldorf, Maryland St. Charles High School (Minnesota), public school in St. Charles, Minnesota St. Charles High School (Missouri), public school in St. Charles, Missouri St. Charles West High School, public school in St. Charles, Missouri Saint Charles Preparatory School, Catholic private school in Columbus, Ohio
See also Saint Charles (disambiguation)