Misterioso means mysterious in the Italian language, and in the context of written music, is an instruction to the performer to play the music in a mysterious mood. It may also refer to:
"Misterioso", a composition by jazz pianist Thelonious Monk and the title for two of his albums Misterioso (Thelonious Monk album), 1958 Misterioso (Recorded on Tour), 1965 Misterioso, a 1991 TV film with Suzan Sylvester and Jack Shepherd, in which the eponymous Monk piece features prominently; aired as part of The Play on One series on BBC One. Misterioso (Paul Motian album), 1987 Misterioso (wrestler) (born 1966), Mexican-American professional wrestler Misterioso, Jr., Mexican masked professional wrestler Misterioso (novel), by Arne Dahl Misterioso (film), a TV film based on the novel
See also "Misteryoso", a 2024 single by Filipino pop/rock band Cup of Joe